Age-related reorganization of corticomuscular connectivity during locomotor perturbations.

Age-related Reorganization of Corticomuscular Connectivity During Locomotor Perturbations

How does the brain communicate with muscles during unexpected perturbations, and how does this change with age? We investigated corticomuscular connectivity during perturbed recumbent stepping in young and older adults using high-density EEG and EMG. Young adults demonstrated selective connectivity between error-processing brain regions and specific muscles, with strong involvement of the anterior cingulate cortex. In contrast, older adults showed elevated baseline connectivity and relied on diffuse patterns dominated by motor and posterior parietal cortices, connecting to multiple muscles simultaneously regardless of their biomechanical role. This reveals a strategic reorganization: young adults use dynamic, error-driven control, while older adults employ a stability-focused approach that maintains comparable performance through constitutive hyperconnectivity. These distinct connectivity signatures establish perturbed recumbent stepping as a valuable tool for assessing age-related sensorimotor changes and developing targeted rehabilitation interventions.

The overall design of the Lab Streaming Layer (LSL) for synchronized data recording.

The Lab Streaming Layer for Synchronized Multimodal Recording

The Lab Streaming Layer (LSL) presents a software-based solution for synchronizing data streams across multiple instruments in neurophysiological research. Utilizing per-sample time stamps and LAN-based time synchronization, LSL ensures accurate, continuous recording despite varying device clocks. It automatically corrects for network delays and jitters, maintaining data integrity through disruptions. Supporting over 150 device classes and compatible with numerous programming languages, LSL has become a vital tool for integrating diverse data acquisition systems. Its robustness and adaptability have extended its application beyond research, into art, performance, and commercial realms, making it a cornerstone for multimodal data collection and synchronization.

NEMAR Dataset Citations Analysis Dashboard

NEMAR Dataset Citations Analysis Dashboard

This dashboard provides comprehensive analysis of dataset citations within the NEMAR ecosystem, revealing collaboration patterns, research trends, and the impact of open neuroscience data sharing on the research community.

HBN Data Insights Dashboard

HBN Dataset Insights Dashboard

This is a data visualization dashboard for exploring the Healthy Brain Network EEG dataset. Features age and sex distributions, task availability metrics, mental health correlations, and per-release analysis across 11 dataset releases with over 3,600 participants.

Topographic maps showing how μECoG at Motor Cortex projects across the scalp

Simulating Scalp EEG from Ultrahigh-Density ECoG Data Illustrates Cortex to Scalp Projection Patterns

Using 1024-electrode ultrahigh-density electrocorticography (μECoG) data as ground truth, this study demonstrates that cortical activity from a small 3×3 cm patch projects broadly across the entire scalp surface, not just to nearby EEG electrodes. By applying ICA decomposition and forward-projecting through a high-definition head model, we show that scalp EEG channels reflect complex mixtures of distributed cortical sources rather than primarily local activity. These findings challenge conventional channel-level EEG interpretation approaches and underscore the critical importance of source-level analysis methods for accurate understanding of brain electrical activity.

Participants per Task and Release Overview

HBN-EEG: Healthy Brain Network EEG Datasets

The Healthy Brain Network EEG Datasets (HBN-EEG) includes 11 dataset releases containing EEG, behavioral data, and rich event annotations from participants aged 5-21 years, supporting large-scale analyses and machine-learning research on mental health.

HBN-EEG dataset

HBN-EEG: The FAIR implementation of the Healthy Brain Network (HBN) electroencephalography dataset

The HBN-EEG dataset provides a comprehensive collection of high-density EEG recordings from the Healthy Brain Network project, formatted in the Brain Imaging Data Structure (BIDS) standard. This dataset includes annotated behavioral and task-condition events, making it ready for various types of analysis without the need for extensive preprocessing. With data from over 2,600 participants, the HBN-EEG dataset supports the development and validation of EEG analysis methods, including machine learning and deep learning approaches. Additionally, it aims to facilitate the creation of EEG-based biomarkers for psychiatric disorders, offering valuable insights into brain function and mental health.

Dual-layer electrode structure for biosignal detection and noise cancellation.

System and methods for biosignal detection and active noise cancellation

We developed a novel EEG system with a dual-electrode net structure for noise reduction and precise biosignal capture. Incorporating advanced software for signal processing, this invention enhances EEG accuracy, reduces setup complexity, and broadens EEG applications, including brain-computer interfaces, through real-time noise separation and immersive noise layering techniques.

Re-referencing methods comparison

Re-Referencing Methods for High-Density EEG

This project investigates different re-referencing approaches for high-density EEG recordings, evaluating their effectiveness in reducing artifacts and improving source localization accuracy. The work contributes to best practices for EEG preprocessing pipelines.

Cortical areas active in response to mechanical perturbations during seated locomotor tasks

Differential Theta-Band Signatures of the Anterior Cingulate and Motor Cortices During Seated Locomotor Perturbations

We demonstrate that seated locomotor perturbations produce differential theta-band responses in the anterior cingulate and supplementary motor areas, suggesting that tuning perturbation parameters can potentially modify electrocortical responses.